New products || Human SARS-CoV-2 (2019-nCoV) project

2020-04-23

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus strain that causes coronavirus disease 2019 (COVID-19), a respiratory illness. It is colloquially known as the coronavirus, and was previously referred to by its provisional name 2019 novel coronavirus (2019-nCoV). SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is contagious in humans, and the World Health Organization (WHO) has designated the ongoing pandemic of COVID-19 a Public Health Emergency of International Concern. 
Taxonomically, SARS-CoV-2 is a strain of severe acute respiratory syndrome-related coronavirus (SARSr-CoV). It is believed to have zoonotic origins and has close genetic similarity to bat coronaviruses, suggesting it emerged from a bat-borne virus. An intermediate animal reservoir such as a pangolin is also thought to be involved in its introduction to humans. The virus shows little genetic diversity, indicating that the spillover event introducing SARS-CoV-2 to humans is likely to have occurred in late 2019. 
Epidemiological studies estimate each infection results in 1.4 to 3.9 new ones when no members of the community are immune and no preventive measures taken. The virus is primarily spread between people through close contact and via respiratory droplets produced from coughs or sneezes. It mainly enters human cells by binding to the receptor angiotensin converting enzyme 2 (ACE2). 
In order to cope with the outbreak of 2019-nCoV epidemic, Abebio started scientific research on novel coronavirus ((2019-nCoV)), and successfully developed the following new product to accelerate researchers’ study on SARS-CoV-2 (2019-nCoV).
 
New products 
 

Recombinant SARS-CoV-2 (2019-nCoV) N protein (Research use only)

Catalog No.

AP50283HU

Product Name

Recombinant Human Novel Coronavirus Nucleoprotein (N) Protein

Sequences

1-419 AA

Tag

with N-terminal 6×His-tagged

MW

48 kDa

Purity

> 90 % as determined by SDS-PAGE

 
Recombinant SARS-CoV-2 (2019-nCoV) S protein (Research use only)

Catalog No.

AP50281HU

Product Name

Recombinant Human Novel Coronavirus Spike glycoprotein (S) Protein

Sequences

16-685 AA

Tag

with N-terminal 10×His-tagged and C-terminal Myc-tagged

MW

82.5 kDa

Purity

> 85 % as determined by SDS-PAGE

 

Catalog No.

AP50282HU

Product Name

Recombinant Human Novel Coronavirus Spike glycoprotein (S) Protein

Sequences

319-541 AA

Tag

with N-terminal 6×His-tagged

MW

28 kDa

Purity

> 90 % as determined by SDS-PAGE

 
SARS-CoV-2 (2019-nCoV) N protein antibody (Research use only) 

Catalog No.

PA82333HU

Product Name

Rabbit anti-Human Novel Coronavirus Nucleoprotein (N) PolyClonal antibody

Antibody type

Rabbit Polyclonal Antibody

Purification

Affinity-purified from rabbit antiserum by Protein A

MW

46 kDa

Applications

ELISA=1:5000-10000; WB=1:500-2000

 

Catalog No.

MA82272HU

Product Name

Mouse anti-Human Novel Coronavirus Nucleoprotein (N) Monoclonal antibody

Antibody type

Mouse Monoclonal Antibody

Purification

Affinity-purified from mouse antiserum by Protein G

MW

46 kDa

Applications

ELISA=1:5000-10000; WB=1:500-2000

 
SARS-CoV-2 (2019-nCoV) N protein IgG antibody ELISA Kit (Research use only) 

Catalog No.

AE64577HU

Product Name

Human Novel Coronavirus Nucleoprotein IgG antibody (2019-nCoV-Ab-IgG) ELISA Kit

Application methods

Qualitative

Sample Type

Serum sample

Dilution factor

201-fold

 

Criterion

ODnegative < 0.21; ODpositive  0.4

While ODsample / ODnegative  2.1: Positive

While ODsample / ODnegative < 2.1: Negative

 
SARS-CoV-2 (2019-nCoV) N protein IgM antibody ELISA Kit (Research use only) 

Catalog No.

AE64578HU

Product Name

Human Novel Coronavirus Nucleoprotein IgM antibody (2019-nCoV-Ab-IgM) ELISA Kit

Application methods

Qualitative

Sample Type

Serum sample

Dilution factor

101-fold

 

Criterion

ODnegative < 0.21; ODpositive  0.4

While ODsample / ODnegative  2.1: Positive

While ODsample / ODnegative < 2.1: Negative

 
SARS-CoV-2 (2019-nCoV) N protein IgA antibody ELISA Kit (Research use only)  

Catalog No.

AE64579HU

Product Name

Human Novel Coronavirus Nucleoprotein IgA antibody (2019-nCoV-Ab-IgA) ELISA Kit

Application methods

Qualitative

Sample Type

Serum sample

Dilution factor

101-fold

 

Criterion

ODnegative < 0.21; ODpositive  0.4

While ODsample / ODnegative  2.1: Positive

While ODsample / ODnegative < 2.1: Negative