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Rabbit Anti-Human Robo3 Polyclonal Antibody

  • Cat.No.: PA91402HU

  • Reactivity: Human

To Purchase PA91402HU

Size:
100μg
Price: Inquire

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Product Details

Species Reactivity Human
UniProt Polyclonal antibody preparation
Host Rabbit
Synonyms RIG1; HGPPS; RBIG1; HGPS; Horizontal Gaze Palsy With Progressive Scoliosis; Roundabout-like protein 3
Concentration 1 mg/mL
Form Lyophilized or Liquid
Purity ≥90% by SDS-PAGE
Molecular Mass 152 kD
Ig Type IgG
Purification Rabbit Polyclonal IgG, affinity purified by Protein A.
Label None
Immunogen Synthesized peptide derived from part region of human protein.
Applications WB; ELISA

Product Overview

ROBO3 is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1.
 

Specifity

ROBO3 Polyclonal Antibody detects endogenous levels of protein.
 

Usage

WB 1:500-2000 ELISA 1:5000-20000; Not yet tested in other applications.
 

Stability

Store at -20°C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-8°C.
 

Storage

Shipped at 2-8°C. Upon delivery aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
 

Stroage Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
 

Precautions

This product is for research use only, not for diagnostic or therapeutic use.