Rabbit Anti-Human Dok-6 Polyclonal Antibody

  • Cat.No.: PA85948HU

  • Reactivity: Human (Homo sapiens)

To Purchase PA85948HU

100μg 500μg
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Product Details

Species Reactivity Human (Homo sapiens)
Source Polyclonal antibody preparation
Host Rabbit
Synonyms DOK5L; Downstream of tyrosine kinase 6; Docking Protein 6; DOK6.
Concentration 1 mg/mL
Form Lyophilized or Liquid
Purity > 90% as determined by SDS-PAGE
Molecular Mass 43 kDa
Ig Type IgG
Purification Rabbit Polyclonal IgG, the antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Label None
Immunogen The antiserum was produced against synthesized peptide derived from human Dok-6. AA range: 111-160 (Q6PKX4).
Applications WB; IHC; IF; ELISA

Product Overview

DOK6 shares 75% and 78% identity with Dok4 and Dok5, respectively, over the PH and PTB domains and also shares a C-terminal region motif that may distinguish this subclass of DOK proteins. RT-PCR analysis of human tissues detected highest expression in the CNS, especially in fetal brain, and high expression in kidney and testis, as well as several Ret-positive neuroblastoma cell lines. In situ hybridization of mouse embryos detected Dok6 expression in the developing neocortex, diencephalon, and spinal cord, as well as in uteric buds of the developing kidney, and in the cranial parasympathetic, sensory, and sympathetic ganglia and the facial motor nucleus. The distribution of Dok6 developmental expression overlapped with Ret expression.



Dok-6 Polyclonal Antibody detects endogenous levels of Dok-6 protein.


ELISA=1:2000-10000; WB=1:500-2000; IHC=1:100-300; IF=1:200-1000. Not yet tested in other applications. 



Store at -20°C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-8°C.



Shipped at 2-8°C, Store it under sterile conditions at -20°C to -80°C upon receiving. **Avoid repeated freeze-thaw cycles.**


Stroage Buffer

0.01M PBS (pH 7.4) with 0.5% BSA, 50% glycerol and 0.02% sodium azide.


This product is for research use only, not for diagnostic or therapeutic use.
  1. Comprehensive Analysis of DOK Family Genes Expression, Immune Characteristics, and Drug Sensitivity in Human Tumors IF: 6.992
    DOK is a new type of regulatory protein family that participates in the regulation of tumor cell growth. However, most of the studies are conducted in cell lines, and systematic studies have not been conducted in human tumors.