Product Details
| Species Reactivity |
Human |
| Source |
Prokaryotic expression |
| Host |
E. coli |
| Synonyms |
Apo-E; APOE; ApoE |
| Concentration |
1 mg/mL |
| Form |
Lyophilized or Liquid |
| Purity |
> 90% as determined by SDS-PAGE |
| Residues |
Lys19~Gln181 (P02649) |
| Tag |
N-terminal His-tag |
| Purification |
Affinity purification |
| Molecular Weight(MW) |
20 kDa |
| Applications |
Western blotting,ELISA;SDS-PAGE;Antigen; |
Product Overview
Apolipoprotein E (ApoE) is a class of apolipoprotein found in the chylomicron and Intermediate-density lipoprotein (IDLs) that is essential for the normal catabolism of triglyceride-rich lipoprotein constituents.[1] In peripheral tissues, ApoE is primarily produced by the liver and macrophages, and mediates cholesterol metabolism in an isoform-dependent manner. In the central nervous system, ApoE is mainly produced by astrocytes, and transports cholesterol to neurons via ApoE receptors, which are members of the low density lipoprotein receptor gene family.
Usage
Reconstitute in PBS or others.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
Stroage Buffer
Lyophilized from 20mM PB, 300mMNaCl，pH7.7
Precautions
This product is for research use only, not for diagnostic or therapeutic use.
Phone: 
E-mail: 
Address: