Recombinant Human Amyloid beta A4 protein (APP) Protein

  • Cat.No.: AP50220HU

  • Reactivity: Human

To Purchase AP50220HU

100μg 500μg
Price: Inquire


Product Details

Species Reactivity Human
Source Prokaryotic expression
Host E. coli
Synonyms ABPP; APPI; APP; A4; AD1
Concentration 1 mg/mL
Form Lyophilized or Liquid
Purity > 90% as determined by SDS-PAGE
Residues Trp97-Leu128 (P05067)
Tag N-GST.tag and C-His.tag
Purification Affinity purification
Molecular Weight(MW) 32 kDa
Applications Western blotting,ELISA;SDS-PAGE;Antigen;

Product Overview

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction.


Reconstitute in PBS or others.


The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.


Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.

Stroage Buffer

Lyophilized from 50mM Tris-cl, 300mM NaCl,pH 9.0


This product is for research use only, not for diagnostic or therapeutic use.